Medicina

This book is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. It provides cutting edge information about fundamental mechanisms underlying neurological diseases. It is amply supplied with tables, illustrations and references. It includes supporting clinical information putting the mechanisms of disease into perspective.

This book details topics of particular importance to critical care cardiovascular diagnosis and management in the perioperative period. It represents an important update for anaesthesiologists, cardiologists, cardiac surgeons, emergency care physicians and intensivists caring for patients with acute, life-threatening cardiovascular afflictions

The first in-depth guide to anesthesia in the geriatric patient Geriatric Anesthesia is the one-of-a-kind guide that reviews everything you need to know about anesthetics in the aged, including palliative care, pain, and polypharmacy. Essential reading for anesthesiologists and geriatricians, this timely reference delivers a detailed overview of both the basic science and practical, day-to-day clinical issues related to the administration of anesthesia in geriatric patients. Geriatric Anesthesia begins with a look at the demographics and economic issues surrounding surgery and anesthesia in the elderly, plus the effects of aging on organ reserve. It then considers geriatric anesthetic implications across the full spectrum of organ systems-from the central/peripheral nervous system to the urinary/hepatic systems. Features Expert authorship-a majority of the authors are from the prestigious Johns Hopkins School of Medicine Department of Anesthesia Full discussion of pharmacology A key section on preoperative assessment, including guidelines on age and anesthetic risk, functional and nutritional status, polypharmacy An insightful review of controversies in intraoperative management, such as the role of invasive monitoring in the elderly, thermoregulation, and hemodilution, prophylactic beta blockade, and regional vs. general anesthesia in achieving successful surgical outcome Postoperative issues, from delirium/postoperative cognitive dysfunction to the assessment and management of chronic pain and palliative care Essential coverage of special topics-perioperative care of the patient with dementia/cognitive dysfunction and medical ethics, including end-of-life care Easy-to-understand tables and 100 line drawings that visually drive home key concepts throughout

The fully updated Crisis Management in Anesthesiology continues to provide updated insights on the latest theories, principles, and practices in anesthesiology. From anesthesiologists and nurse anesthetists to emergency physicians and residents, this medical reference book will effectively prepare you to handle any critical incident during anesthesia.

"NMS Emergency Medicine, Second Edition" provides medical students, residents, physician assistants, and nurse practitioners with an introduction to the core content of emergency medicine. The book's concise narrative outline format helps readers quickly assimilate large amounts of material. Each chapter is followed by USMLE-style study questions. A comprehensive Board simulation examination is offered online. This edition has been thoroughly updated and streamlined to focus on essential material. Questions have been revised to better reflect the level of difficulty of shelf exams. The book has a new two-color design with more illustrations and wider margins for notes.

Written by a pre-eminent educator in radiology, "Musculoskeletal Imaging Companion, Second Edition" is a practical quick-reference guide to the radiologic diagnosis of musculoskeletal disorders. It presents nearly 1,400 large, clear images of common diseases, disorders, and injuries, accompanied by succinct, bulleted "key facts" about the clinical and imaging features of each condition. Chapters cover all anatomic regions and disease entities, imaging of orthopaedic appliances and prostheses, and detailed protocols for all current imaging modalities, now including PET. The book demonstrates the utility of multiple modalities in specific situations and recommends the best, most cost-effective approach. This updated edition includes over 200 new images and numerous new disorders.

This book takes you through the fundamental principles of haematology and immunology in a comprehensive yet concise format. Each discipline is considered in an integrated format, combining histology, physiology, and pharmacology. The basic pathology of haematology and immunology is then outlined, highlighting the more common diseases and investigations. "Crash Course: Immunology and Haematology" covers the latest information in both fields, including advances in understanding innate immunity and in the use of therapeutic monoclonal antibodies.

This book is a compilation of readings representing the basis for the practice of pediatric audiology. It contains forty-seven selected articles that are considered critical to understanding the fundamental principles in the field. Divided into five sections, the book covers the development of audition in infants, background information for current practice, test techniques and technology, and hearing loss in special populations. The readings in this book provide a foundation of knowledge that should be considered essential for anyone in the field of pediatric audiology.

The revised and updated second edition of this comprehensive text continues to offer careful critical evaluation and authoritative advice on stroke, the most complicated disease affecting the nervous system of children and young adults. New chapters, the latest guidelines from the American Heart Association, tips for preventing misdiagnoses, and more provide you with the knowledge you need to make the best clinical and management decisions of both common and rare cerebrovascular disorders in the young population. Tightly focused, this fully referenced textbook fills the void in the literature by including detailed discussions on topics such as stroke in neonates, atherosclerotic cerebral infarction in young adults, strokes caused by migraines, stroke during pregnancy, and a myriad of others. Up-to-date tables containing rich troves of data along with the careful selection of multiple references further enhances your acumen.

Established for forty years as the definitive reference on lupus, Dubois' Lupus Erythematosus is now in its thoroughly revised, updated Seventh Edition. More than ninety distinguished contributing authors--twenty of them new to this edition--provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. New chapters cover cytokines and interferons, pathogenesis of atherosclerosis, immune tolerance, clinical indices in assessment of lupus, mixed connective tissue disease, reproductive issues, fibromyalgia, gender-related issues, and biomarkers.

"Nutrition Essentials and Diet Therapy, 10th Edition" provides an updated, concise, and practical approach to basic health care nutrition. This versatile text concentrates on what is most important for the health care provider to know about the nutrition basics and the application on nutrition knowledge. Content coverage includes the latest developments in nutrition fundamentals, nutrition across the life span, nutritional management of chronic and acute illnesses, and expanded coverage of vitamins, minerals, phytochemicals and herbal remedies.

Widely acknowledged as one of the most challenging aspects of dealing with an ageing population, the increasing prevalence of cognitive decline in the elderly presents the clinician with a variety of complex therapeutic problems. Alzheimer's disease and other dementias vary in their onset and progression, as do patients in their responsiveness to treatment. Social management is as important as the choice of therapeutic agent, and implementing effective and sympathetic treatment requires care and sensitivity as well as a sound knowledge of currently available options. In this important new work, leading experts review the therapeutic agents currently available and assess their effectiveness. Also included is an update on recent and on-going clinical trials, the prospects for new therapeutic targets and the development of new biomarkers that will aid recognition of disease and thus earlier intervention.

Finally, a pacing book dedicated to the adult patient with CHD. Drawing on their vast experience, Drs. Mond and Karpawich join forces to show you what to do, how to do it, and what to avoid. Building on more than 60 years of device therapy Pacing Options in the Adult Patient with Congenital Heart Disease leads you through the many congenital heart defects now seen in adults. This essential resource: * Describes the various anatomical characteristics of repaired and non-repaired congenital heart defects and compares these with the normal anatomy, allowing you to easily identify the differences * Guides you through the implant techniques, highlighting the specific problems that might be encountered and providing proven techniques to overcome technically difficult anatomical variations in patients with and without congenital heart disease Throughout the book, schematic diagrams of the diverse anatomy of the congenital heart support the textual descriptions, and x-rays and fluoroscopic images illustrate the physiology and maximize understanding.

Although vitiligo has traditionally been very difficult to treat, a new breakthrough surgical treatment is expanding options for practitioners and patients. Standard treatments depend on the severity of the condition and the patient's feelings of disfigurement. Cover-up cosmetics work well for some people. Other more sophisticated forms of treatment include gradually developing color back in the depigmented areas (repigmentation) by PUVA or other ultraviolet light treatments, but this is extremely slow and intensive, often requiring several hundred treatments. This new form of treatment, which involves surgically transplanting melanocytes into the white areas, is most successful in patients with stable vitiligo over less than 30% of their body surface area. It complements medical therapies in achieving complete and sustained repigmentation and is rapidly gaining popularity in all major centers. This is the first book available which describes this major advance in detail. * Explains the new treatment of surgically transplanting melanocytes into the affected areas of the skin to provide dermatologists and surgeons with the latest state-of-the-art information * Written by the international leaders who pioneered this treatment * Presents all the latest information on the topic, eliminating the need to search through multiple sources for specific data

The efficient delivery of cellular constituents to their proper location is of fundamental importance for all cells and is of particular interest to neuroscientists, because of the unique functions and complex architecture of neurons. Protein Trafficking in Neurons examines mechanisms of protein trafficking and the role of trafficking in neuronal functioning from development to plasticity to disease. The book is divided into seven sections that review mechanisms of protein transport, the role of protein trafficking in synapse formation, exo- and endocytosis, transport of receptors, trafficking of ion channels and transporters, comparison of trafficking mechanisms in neuronal vs. non-neuronal cell types, and the relationship between trafficking and neuronal diseases such as Alzheimer's, Huntington's and Prion Diseases. Provides a comprehensive examination of membrane/protein movement in neuronal function. Sections on synapse development, synaptic transmission, and the role of trafficking in neurological disease Includes a focus on Molecular Mechanisms Illustrated with color summary pictures The only book examining protein trafficking and its functional implications, written by leaders in the field