Genetica
Tutti i libri di Genetica - Pagina 9
Mouse Phenotypes
An Handbook of Mutation Analysis
Papaionnou, V. E. , Behringer, R. B.
editore: Cshl Press
pagine: 234
The Inside Story: DNA to RNA to Protein
Readings from trends in biochemical sciences
Witkowski. J.
editore: Cshl Press
pagine: 380
Whole Genome Amplification
Methods Express
Hughes, S. , Lasken, R.
editore: Scion Publishing LTD
pagine: 192
Genetics for Pediatricians
The Molecular Genetic Basis of Pediatric Disorders
Ian Young , Mohnish Suri
editore: ReMedica
pagine: 250
Genetic testing now plays an important role in the investigation of almost every child who is presented with one of the many commonly inherited disorders that make a major contribution to pediatric morbidity and mortality throughout the world. It can be difficult for even the most conscientious practitioner to keep abreast of developments and to appreciate both the significance and relevance of some of the major discoveries of recent years. The number of conditions that have been mapped or in which the causative gene has been isolated is vast. This book restricts coverage to the more common single-gene disorders that are likely to be encountered in general pediatric practice, with particular attention focused on those in which molecular analysis can play an important role in the diagnosis or management of a child and his or her family.
The Human Genome
A User's Guide
Catherine A. Mori
,
Julia E. Richards
e altri
editore: Academic Press Inc
pagine: 480
This second edition of a very successful text reflects the tremendous pace of human genetics research and the demands that it places on society to understand and absorb its basic implications. The human genome has now been officially mapped and the cloning of animals is becoming a commonplace scientific discussion on the evening news. Join authors Julia Richards and Scott Hawley as they examine the biological foundations of humanity, looking at the science behind the sensation and the current and potential impact of the study of the genome on our society. The "Human Genome, Second Edition" is ideal for students and non-professionals, but will also serve as a fitting guide for the novice geneticist by providing a scientific, humanistic, and ethical frame of reference for a more detailed study of genetics. This edition has 60 per cent new material, including data from the Human Genome Project and the latest genetics and ethics discussions. Several new case studies and personal stories bring the concepts of genetics and heredity to life. There is simplified treatment of material for non-biology majors. There is new full-color art throughout the text.
New co-author, Julia Richards, joins R. Scott Hawley in this revision.
Genetic Predisposition to Cancer
B. A. J. Ponder
,
Charis Eng
e altri
editore: Hodder Arnold
pagine: 466
Over the last 20 years it has become increasingly apparent that the occurrence of many cancers can have an inherited basis. This book examines the principles underlying genetic predisposition to cancer and will be relevant to practising oncologists, geneticists and other professionals interested in this rapidly expanding field. Coverage is comprehensive, taking the reader from an introduction to genetic predisposition, through a discussion of the molecular biology and statistical techniques involved in the identification and characterisation of predisposition genes, to a consideration of heritable cancer syndromes, and encompasses both rare and common cancers. The text also features a discussion of cancer risk assessment, genetic counselling issues, genetic screening and cancer management options, and a consideration of the associated ethical and psychological issues. Building on the reputation of the previous edition, and to reflect the rapid advances in the field since its publication, the contents of the second edition have been thoroughly updated and include discussion of many newly identified cancer genes.
In particular, the book features new chapters added on the biological basis of cancer predisposition, population-based studies of susceptibility, and evaluation of management strategies for individuals at increased cancer risk.
Is it in Your Genes?
The Influence of Genes on Common Disorders and Diseases That Affect You and Your Family
Philip R. Reilly
editore: Cold Spring Harbor Laboratory Press,U.S.
pagine: 304
It is now clear that our risk of developing almost any disease is influenced by the genes with which we are born. One of the most important dividends of the Human Genome Project will be a much greater understanding of the influence of genes on disease and disorders in children (from asthma to autism) and adults (including heart disease, virtually all cancers, and Alzheimer's disease). The nature of genetic risks in families is becoming clearer and this book is written to help people understand them. Philip Reilly, a physician-geneticist, who has given hundreds of lectures on this subject, takes a user-friendly approach. Drawing on the many questions he has been asked (for example, My sister has multiple sclerosis. Am I at an increased risk?”), Reilly discusses over 90 common conditions, diseases, and disorders, arranged from conception to old age. In frank, non-technical terms, he makes clear what is known and not known about the genetic factors and, if your risk is elevated, what you might be able to do about it. This book is a uniquely valuable resource for anyone seeking more information about a family's disease heritage.
Hereditary Hearing Loss and Its Syndromes
Helga V. Toriello
,
Robert J. Gorlin
e altri
editore: Oxford University Press Inc
pagine: 524
Genetic deafness affects 1 in 1000 children, and over the last decade several dozen of the responsible genes have been identified. This unique textbook aims to assist clinicians dealing with deaf patients and families by critically reviewing all relevant published material on genetics, pathology, clinical presentation, diagnosis, and laboratory findings. Thoroughly revised, the Second Edition has been updated throughout and includes a new chapter on hearing loss with cardiovascular disorders. It continues with the successful formula of presenting separate chapters on deafness associated with findings in specific body systems. Careful attention to cross referencing between chapters means that the multifaceted clinical presentations of distinct conditions are highlighted. These clinical variations are complemented by excellent clinical photographs, audiograms, figures from essential laboratory or other investigations, and comprehensive reference lists. Gene mutations that cause deafness are highlighted throughout the text, both in chapters dealing with syndromes and in a vastly expanded chapter focusing specifically on nonsyndromic forms of deafness. Thus, the new edition reflects all the progress on the molecular understanding of deafness made in recent years and integrates these findings into clinical practice. It also makes an important contribution to the cataloguing of new syndromes that have emerged in recent years, such as HIDS and X-linked maxillofacial dysostosis.
Understanding DNA
The molecule and how it works
Calladine, C. R. , Drew, H. R. , Luisi, B. F. , Travers. A. A.
editore: Academic Press
pagine: 334
Molecular analysis and genome discovery
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Rapley, R. , Harbron, S.
editore: Wiley & sons
pagine: 372
Malattie genetiche. Molecole e geni. Diagnosi, prevenzione e terapia
Antonio Cao
,
Bruno Dalla Piccola
e altri
editore: Piccin-Nuova Libraria
pagine: 882
Cell growth
Control of cell size
Hall, M. N. , Raff, M. , Thomas, G.
editore: Cshl Press
pagine: 652
Purifying Proteins for Proteomics
A Laboratory Manual
Simpson, R. J.
editore: Cshl Press
pagine: 800
Gene Therapy of the Central Nervous System
From Bench to Bedside
Matthew During , Michael G. Kaplitt
editore: Academic Press Inc
pagine: 370
Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. "Gene Therapy of the Central Nervous System: From Bench to Bedside" represents the first definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped create this field and are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects of interest to anyone exploring or using gene therapy for neurobiological applications in research and clinical praxis. This work presents gene transfer technologies with particular emphases upon novel vehicles, immunological issues and the role of gene therapy in stem cells.
It discusses preclinical areas that are likely to translate into clinical studies in the near future, including epilepsy, pain and amyotrophic lateral sclerosis. It includes 'insider' information on technological and regulatory issues which can often limit effective translation of even the most promising idea into clinical use.
The Molecular and Genetic Basis of Neurologic and Psychiatric Disease
Eric J. Nestler
,
Robert L. Barchi
e altri
editore: Butterworth-Heinemann Ltd
pagine: 890
110 of the world's foremost authorities explore the latest advances in molecular and cellular neurobiology and molecular neurogenetics and their implications for the development of pharmacologic or gene therapy for patients with genetic diseases of the nervous system. The 3rd Edition features a new section on psychiatric diseases, 26 additional new chapters, and an even stronger clinical focus, offering practical guidance on a full range of diseases and the roles that molecular biology and genetics play in their diagnosis and management. It includes the latest advances in molecular research.
