Epidemiologia e statistica medica

Il contenuto degli studi pubblicati nelle riviste scientifiche è spesso difficile da capire e la validità dei risultati e dell

Il testo presenta un approccio nuovo alla statistica, basato sull'uso degli intervalli di confidenza invece che su quello dei tradizionali test statistici, ancorati al fatidico valore "p" e alla conseguente dicotomia "significativo/non significativo". Tale approccio rende più facili e comprensibili i principi su cui si basa l'analisi statistica anche ai non specialisti, quelli cioè che si servono della statistica per meglio comprendere la letteratura scientifica o che desiderano elaborare autonomamente i dati delle loro ricerche. Il software che accompagna la pubblicazione, compatibile con Windows, fornisce uno strumento agile da usare per il calcolo di tutti gli intervalli illustrati, secondo i metodi descritti.

La seconda edizione di questo volume per gli studenti dei corsi di laurea triennali per le professioni sanitarie non mediche presenta una revisione globale delle conoscenze di base in campo statistico, soprattutto con un occhio di riguardo alle tematiche che costituiranno i fondamenti degli studi successivi, in particolare gli aspetti relativi alla ricerca quali ad esempio la statistica inferenziale e il campionamento.

Blackwell Publishing is delighted to announce that this book has been Highly Commended in the 2004 BMA Medical Book Competition. Here is the judges' summary of this book: "This is a technical book on a technical subject but presented in a delightful way. There are many books on statistics for doctors but there are few that are excellent and this is certainly one of them. Statistics is not an easy subject to teach or write about. The authors have succeeded in producing a book that is as good as it can get. For the keen student who does not want a book for mathematicians, this is an excellent first book on medical statistics." Essential Medical Statistics is a classic amongst medical statisticians. An introductory textbook, it presents statistics with a clarity and logic that demystifies the subject, while providing a comprehensive coverage of advanced as well as basic methods. The second edition of Essential Medical Statistics has been comprehensively revised and updated to include modern statistical methods and modern approaches to statistical analysis, while retaining the approachable and non-mathematical style of the first edition. The book now includes full coverage of the most commonly used regression models, multiple linear regression, logistic regression, Poisson regression and Cox regression, as well as a chapter on general issues in regression modelling. In addition, new chapters introduce more advanced topics such as meta-analysis, likelihood, bootstrapping and robust standard errors, and analysis of clustered data. Aimed at students of medical statistics, medical researchers, public health practitioners and practising clinicians using statistics in their daily work, the book is designed as both a teaching and a reference text. The format of the book is clear with highlighted formulae and worked examples, so that all concepts are presented in a simple, practical and easy-to-understand way. The second edition enhances the emphasis on choice of appropriate methods with new chapters on strategies for analysis and measures of association and impact. Essential Medical Statistics is supported by a web site at www.blackwellpublishing.com/essentialmedstats. This useful online resource provides statistical datasets to download, as well as sample chapters and future updates.

Field epidemiology involves the application of epidemiologic methods to unexpected health problems when a rapid on-site investigation is necessary for timely intervention. Based on decades of experience in both infectious and non-infectious diseases at the Centers for Disease Control and Prevention, this book describes in simple and practical terms the distinct approach, tasks, and actions needed for successful field investigations. Guidance is given on such issues as how to perform surveillance, manage and execute field investigations, collect and analyze data, perform surveys, adapt a personal computer for field use, and communicate the findings. Specific advice is also given on such subjects as dealing with the media; investigations in healthcare, day-care, and international settings; and the legal aspects of field studies. An entire chapter covers the proper collection, handling, and testing of infectious and non-infectious agents in the field. In the Second Edition, four new chapters cover many unique aspects of field studies in the workplace, after natural disasters, in preparation for and response to possible bioterrorist attacks, and by state and local health departments. Finally, an appendix describes how to investigate a common source food-borne epidemic. This text gives public health professionals and students a practical and complete reference to use in virtually any field investigation setting.

The basis for much of medical public health practice comes from epidemiological research. This text describes current statistical tools that are used to analyse the association between possible risk factors and the actual risk of disease. Beginning with a broad conceptual framework on the disease process, it describes commonly used techniques for analysing proportions and disease rates. These are then extended to model fitting, and the common threads of logic that bind the two analytic strategies together are revealed. Each chapter provides a descriptive rationale for the method, a worked example using data from a published study, and an exercise that allows the reader to practice the technique. Each chapter also includes an appendix that provides further details on the theoretical underpinnings of the method. Among the topics covered are Mantel-Haenszel methods, rates, survival analysis, logistic regression, and generalised linear models. Methods for incorporating aspects of study design, such as matching, into the analysis are discussed, and guidance is given for determining the power or the sample size requirements of a study. This text will give readers a foundation in applied statistics and the concepts of model fitting to develop skills in the analysis of epidemiological data.

The term "communicable disease control" describes the way in which outbreaks of infectious diseases are managed to prevent their transmission and spread. This includes surveillance, prevention, investigation and response to cases. This book is a practical guide. In Europe the range of diseases and infectious agents differs from that of the US, and yet the only real reference in this field is an American book: "Benenson: Control of Communicable Disease Manual". This is published by the American Public Health Association every five years and is considered to be a good resource. The problem is that it covers many diseases that do not occur in Europe and omits a number of important European infections. Furthermore, the epidemiological information it gives is based on the US population. It does not consider the public health issues in a European and UK context. This volume aims to fill the gap in the European market.

Cancer screening programmes have become routine practice throughout the developed world -- aiming to detect the presence of the disease prior to the manifestation of symptoms, and to increase the likelihood of successful treatment. Naturally, these programmes require regular monitoring to ensure that screening quality is maintained, and to advance the early-warning system as much as possible. Quantitative Methods for the Evaluation of Cancer Screening is a professional title designed to provide the researchers of these screening programmes with up-to-date methods and tools for improving evaluation. The book presents an introduction to cancer screening and to the methods that are employed for its monitoring, followed by an in-depth account of the more complicated modelling approaches. Each chapter is written by an international expert in the field, and imparts practical specialist information that the reader can apply to the evaluation of their own programmes. Case studies illustrate the methods in practice and provide further illumination of the fields of breast, cervix, large bowel, and neuroblastoma screening.

Il saggio tratta i rapporti tra bevande alcoliche e salute affrontando in modo sintetico e chiaro i seguenti argomenti. Panoramica epidemiologica nel mondo e in Italia, excursus aggiornato delle principali malattie alcol correlate, effetti del metabolismo dell’alcol sull’organismo e sul cervello, le frequenti urgenze mediche intossicazione alcolica acuta e sindrome da astinenza, con cenni sul loro trattamento, le evidenze di associazione causale alcol e tumori, il complesso e controverso rapporto tra alcol e malattie cardiovascolari, le conseguenze dell’uso di alcol in gravidanza e allattamento, il problema alcol e lavoro, l’interazione alcol e farmaci ed infine la terapia e la riabilitazione dell’alcolismo e le politiche sanitarie di prevenzione primaria in tema di alcol. Le acquisizioni sui singoli temi specifici saranno di interesse per alcune categorie di lettori ma anche per il lettore semplicemente curioso di addentrarsi nell’argomento. Le nozioni, confermate dalla letteratura scientifica più autorevole sono corroborate da una lunga e pregnante esperienza, vissuta sul campo.

Written by renowned epidemiologists and public health experts, this unique text provides complete, concise coverage of epidemiology, biostatistics, preventive medicine, and public health in clear, easy-to-understand terms. One convenient volume delivers must-know content in four complex areas-information that’s sure to be covered in today’s classrooms and on USMLE exams-presented with a clinical focus and real-life medical examples throughout. Depth of coverage, concise writing style, outstanding online review questions, a clinical emphasis … these features and more make Jekel's your go-to resource for learning, study, and review. Focuses on clinical problem solving and decision making using epidemiologic concepts and examples Contains more clinical cases throughout, including global examples. Offers expanded coverage of the impact of big data and precision medicine, as well as an updated and reorganized biostatistics section Features quick-reference boxes that showcase key concepts and calculations, and dynamic illustrations that facilitate learning using a highly visual approach Provides almost 300 multiple-choice chapter review questions and answers in print with additional questions and more online at Student Consult Aligns content to board blueprints for the USMLE as well as the three specialties certified by the American Board of Preventive Medicine: Occupational Medicine, and Public Health & General Preventive Medicine-and is recommended by the ABPM as a top review source for its core specialty examination Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all the text, figures, and references from the book on a variety of devices Evolve Instructor site, with an image and table bank as well as chapter overviews as PowerPoints, is available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com

Questo volume si rivolge agli studenti dei corsi di Matematica e statistica dei corsi di laurea di Scienze. Il testo cerca di spingere lo studente a una lettura attiva, mettendolo nelle condizioni di interagire con quanto studiato in modo da verificare passo passo la comprensione dei concetti attraverso un ricco apparato pedagogico. La copertura degli argomenti comprende quelli trattati in un corso di matematica di base (funzioni e gli strumenti per lo studio delle stesse), quelli di in un corso di probabilità e statistica, senza tralasciare l'algebra lineare. I numerosi esempi tratti dai diversi ambiti delle scienze della vita contribuiscono a rendere la materia più appassionante e vicina al percorso di studi degli studenti per i quali è pensato il volume. Incluso nel testo, un Eserciziario con 750 problemi guida ed esercizi costituisce un utile strumento di apprendimento e autovalutazione. Le soluzioni degli esercizi sono disponibili sul sito web del volume.