Blackwell Science Ltd

The potential capacity of the biphosphonates to intervene in osseous remodeling was recognized more than 30 years ago. The biphosphonates inhibit osteoclastic activity. In spite of advances in early detection, surgey, chemo-and radiotherapy, metastatic bone disease is still a major and in many cases intractable clinical problem. The biphosphonates are now the most effective agents in the management of bone metastases - as shown by trials in patients with breast and prostate cancer, and in multiple myeloma. Bone pain, new ostelytic events and pathologic fractures are decreased and complications associated with these events are avoided. Existing osteolytic lesions may even be reversed. New fields of indications of biphosphonates are shown to be in the adjuvant therapy of breast cancer and in stage 1 multiple myeloma to prevent skeletal destruction and also to inhibit tumor growth. Over the past few years the biphosphonates have proved their value also in many other conditions such as Paget's disease of bone, osseous disorders with an osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic agents will be in these disorders, and particularly in so-called primary osteoporosis which evenually effects anyone who lives long enough, causing widespread morbidity with drastic economic consequences both individually and nationally. The authors' aim is to provide an office and desk companion - comprehensive, concise, practical for easy reference - an up-to-date guide for prevention and therapy of skeletal complications whenever and wherever they occur in general and specialized medical practice.

Using images and anatomic illustrations, Rad Tech's Guide to MRI: Imaging Procedures, Patient Care, and Safety provides the reader with a quick overview of MRI for quick reference and examination preparation. As part of the Rad Tech's Guide Series, this volume features an overview of anatomy, imaging tips, scanning procedures, and the latest information on protocols--all in the context of patient care and safety. Each book in the Rad Tech's Guide Series covers the essential basics for those preparing for their certifying examinations and those already in practice.

This handy reference will give the practicing and training technologist a solid understanding of basic MRI principles on which further learning can be built. Beginning with a hardware overview and moving through tissue characteristics, image quality and flow imaging, Rad Techa s Guide to MRI: Basic Physics, Instrumenation, and Qaulity Control should be used as both an introduction and an examination preparation tool. Each book in the Rad Techa s Guide Series covers the essential basics for those preparing for their certifying examinations and those already in practice.

The distinguishing feature of this book is that the lead author is one of the most eminent hepatologists in the world. He is joined by expert radiologists to produce a book describing the pathophysiology (the effect of disease on normal function) of hepatobiliary diseases. It is NOT a conventional radiology book, nor a conventional hepatology textbook. The objective of this book is to teach an understanding of liver pathophysiology and diagnosis with the aid of imaging.

The purpose of this book is to provide a fundamental understanding of magnetic resonance (MR) imaging. From this, readers will acquire a fundamental knowledge that enables them to pursue studies of their own and to cope with some of the most common problems, such as image contrast and artifacts or questions concerning possible hazards to patients. MR imaging not only requires knowledge of facts, but also some background information for decision-making. This edition, therefore, includes some subjective, critical, and opinion-oriented sections, intended to offset the technical nature of the book and provide some insights into more practical questions faced by MR users. A new addition to this edition is MR Image Expert, an interactive learning and teaching tool for MR which simulates the most important aspects of MR imaging on a personal computer. A further application, Dynalize, is included which allows the presentation and analysis of dynamic MR imaging studies.

The number of ferrets kept as pets is rising each year in Europe and North America. They are ideal companions for those who lead busy lives, since they are friendly, playful and easy to look after. Today, veterinary practices see more ferrets than ever before, for a wide range of diseases as diverse as those seen in the dog and cat, and veterinarians are increasingly called upon to provide advice and treatment for these more unusual pets. This book is intended to be a practical and concise guide to the management of ferret diseases to assist veterinary surgeons and veterinary nurses alike. Information on these animals is seldom available in convenient form elsewhere. This book brings together in one volume a wealth of useful information for all those involved in the care and management of ferrets.