This unique text, authored by the individuals who pioneered the use of Photodynamic Therapy (PDT), is designed to provide clinicians with an understanding of the basic physics of PDT and the rationale and techniques of PDT in ophthalmology and especially in age-related macular degeneration. The different photosensitizers, lasers, and possible future use of this new therapeutic modality for other intraocular pathologies are also discussed. This text offers a step-by-step, detailed approach to the use of PDT, picking up where the scientific journal articles leave off
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Section I: Introduction to Photodynamic Therapy Chapter. 1: History of PDT - E.S. Gragoudas, M.D., J.W. Miller, M.D., L. Zografos, M.D. Chapter. 2: History of PDT - J.W. Miller, M.D., E.S. Gragoudas, M.D. Chapter. 3: Principles of Photodynamic Therapy Section II: Pre-clinical Studies Chapter. 4: In vitro assessment and bioassay of photosensensitizers for ocular PDT Chapter. 5: Combination of PDT and anti-angiogenic drugs Chapter. 6: PDT for experimental choroidal neovascularization using Visudyne Chapter. 7: PDT for experimental choroidal neovascularization using ATX-S10 (Na) Chapter. 8: PDT for experimental choroidal neovascularization using Purlytin Chapter. 9: PDT for experimental choroidal neovascularization using Lu-Tex Chapter. 10: PDT for iris neovascularization Chapter. 11: Recovery after repeated PDT treatments for normal retina and choroid Chapter. 12: The ocular localization of photosensitizers Chapter. 13: PDT of experimental choroidal neovascularization using NP with 6 Chapter. 14: PDT for experimental intraocular tumors Section III: Clinical Studies Chapter. 15: PDT for AMD Part. 1: PDT for age related macular degeneration: How to do it Part. 2: Fluorescein angiography and optical coherence tomography in photodynamic therapy for CNV due to AMD Part. 3: ICG angiography in photodynamic therapy of CNV Part. 4: Subfoveal choroidal blood flow and its regulation After photodynamic therapy in choroidal neovascularization Part. 5: Results of AMD trials using Visudyne; Phase 1 and 2) Part. 6: Results of age related macular degeneration trials with Visudyne (TAP/ VIP) Chapter. 16: Verteporfin PDT in pathologic myopia Chapter. 17: Photodynamic Therapy of CNV CNV From Causes Other Than AMD and Pathologic Myopia Chapter. 18: Verteporfin therapy in clinical practice Chapter. 19: Incidence of eligible cases in clinical practice Chapter. 20: PDT with SnET2 Chapter. 21: PDT with Lutex-early results at one month Section IV: Angiography with photosensitizers Chapter. 22: Angiography With Visudyne Chapter. 23: Angiography with Lu-Tex Chapter. 24: Angiography with other dyes Chapter. 25: Future Direction
