There have been very significant advances across many areas of the study, investigation and treatment of breast cancer. This publication surveys how scientific advances have influenced, improved and extended therapeutic options. The volume spans prevention, screening, genetics, and treatment of pre-invasive breast cancer, before focusing in depth on management of established breast cancer. This includes chapters on the various therapeutic options available and their role in treating breast cancer from the very earliest stage through to advanced and metastatic breast cancer. In addition, the text looks forward at the potential for emerging experimental strategies to become adopted into medical management in the future. The volume concludes with a chapter on palliative care. This wide-ranging account will be essential for breast cancer specialists, trainees in oncology and clinical research scientists.
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List of contributors; 1. History of breast cancer therapy Zenon Rayter; 2. Chemoprevention of breast cancer Tamas Hickish; 3. Familial breast cancer H. Gogas and V. Murday; 4. Hormone replacement therapy and breast cancer J. Marsden and N. P. M. Sacks; 5. Screening for breast cancer Rosalind Given-Wilson; 6. The management of in situ breast cancer Zenon Rayter; 7. Adjuvant systematic therapy T. R. J. Evans; 8. Adjuvant radiotherapy in the management of breast cancer Gillian Ross, David Landau and Andrew Tutt; 9a. Cell kinetic parameters and response to therapy R. S. Camplejohn; 9b. Predictors of response and resistance to medical therapy: endocrine therapy Zenon Rayter; 9c. Predictors of response and resistance to medical therapy: chemotherapy Stephen R. D. Johnson; 10. Primary medical therapy in breast cancer Janine L. Mansi; 11. Medical therapy of advanced disease Alison Jones and Karen McAdam; 12a. High dose chemotherapy in breast cancer John Crown and R. C. F. Leonard; 12b. New immunological approaches to treatment for breast cancer A. G. Dalgleish; 13. The place of bisphosphonates in the management of breast cancer A. H. G. Paterson; 14. Palliative care in breast cancer Janet Hardy; Index.
