Genetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations. The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future. The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors. This will be essential reading for psychiatrists and geneticists and will be of interest to neurologists, psychologists and neuroscientists.
Indice testuale
A - BASIC PRINCIPLES; 1. Basic molecular genetics; 2. Quantitative genetics; 3. Linkage and association; B - THE GENETICS OF NORMAL AND ABNORMAL DEVELOPMENT; 4. Personality and cognitive abilities; 5. Mental retardation; 6. Language disorders; 7. Childhood disorders; C - THE GENETICS OF ABNORMAL BEHAVIOUR IN ADULT LIFE; 8. Personality disorders; 9. Affective disorders; 10. Schizophrenia; 11. Substance misuse; 12. Anxiety and eating disorders; 13. The dementias; D - APPLICATIONS AND IMPLICATIONS; 14. Pharmacogenetics; 15. Genetic counselling; 16. Ethical considerations; 17. The future and post-genomic psychiatry
