Written by distinguished authorities, this volume is a comprehensive text on the mechanisms, diagnosis, and management of paediatric endocrine disorders. It provides exceptional coverage of current scientific concepts and state-of-the-art, practical clinical information. The opening sections examine genetic aspects of endocrinology and diagnostic tests, including imaging and molecular techniques. Subsequent sections cover the hypothalamus and pituitary, growth, sexual differentiation and maturation, glucose homeostasis, the thyroid, the adrenal glands, bone and mineral metabolism, abnormalities of nutrition, and multi-endocrine diseases. Each section progresses from molecular genetics and developmental endocrinology to specific clinical disorders and management strategies. Numerous illustrations highlight key concepts.
Indice testuale
Section I. Genetics in Endocrinology Chapter 1 Monogenic and Polygenic Disorders in Endocrinology John Phillips III and Amy Potter Chapter 2 Genetic Syndromes with Endocrinopathies Patricia Y. Fechner Section II. Evaluation of Endocrine Disorders in Children Chapter 3 Diagnostic Imaging in Pediatric Endocrinology Donald O. Corea, Aslam R. Siddiqui, and Mary K. Edwards-Brown Chapter 4 Molecular Concepts and Techniques in Endocrinology Constantin Polychronakos and Zubin Punthakee Section III. Hypothalamus and Pituitary Chapter 5 Molecular Genetics of Hypothalamic-Pituitary Axis Development Phu V. Tran, Jesse J. Savage, Holly A. Ingraham, and Simon J. Rhodes Chapter 6 Manifestations of Mutations in Pituitary Transcription Factors and Clinical Disorders of the Anterior Pituitary John S. Parks and Milton R. Brown Chapter 7 Clinical Disorders of the Posterior Pituitary Gary L. Robertson Chapter 8 Endocrine Issues in Survivors of Childhood Cancer Thomas Moshang, Jr., and Stuart A. Weinzimer Section IV. Growth Chapter 9 Molecular Mutations in the GH-IGF Axis Zvi Laron Chapter 10 Physiology of the Growth Hormone--IGF Axis Katie Woods and Ron G. Rosenfeld Chapter 11 Clinical Aspects of Growth and Growth Disorders Robert Rapaport and Deborah A. Bowlby Chapter 12 Short Stature and Quality of Life: A Review of Assumptions and Evidence David E. Sandberg, Melissa Colsman, and Linda D. Voss Chapter 13 Turner Syndrome Chapter 14 Endocrinopathies in Infants Who Are Small for Gestational Age Mireya H. Garcia, Radhika H. Muzumdar, and Paul Saenger Section V. Sexual Differentiation and Maturation Chapter 15 Molecular Genetic Control of Sexual Differentiation Mary M. Lee Chapter 16 Intersex Disorders Mary Pat Gallagher and Sharon E. Oberfield Chapter 17 Cryptochidism Chapter 18 Androgens and Behavior: Implications for the Treatment of Children with Disorders of Sexual Differentiation Sheri A. Berenbaum Chapter 19 Control of the Onset of Puberty J. P. Bourguignon Chapter 20 Growth Hormone, Sex Steroids and IGF-I: Metabolic Effects in Puberty and Beyond Nelly Mauras Chapter 21 Precocious Puberty Peter A. Lee and James R. Kerrigan Chapter 22 Delayed Puberty John C. Achermann Chapter 23 Gynecomastia Edward O. Reiter and Glenn D. Braunstein Chapter 24 Hyperandrogenism in Children and Adolescents M. Belen Roldan Martin and Selma Feldman Wichtel Chapter 25 Endocrine Disruptors and Development of the Reproductive System: A Pediatric Perspective Katharina M. Main, Ewa Rajpert-De Meyts, Jorma Toppari, and Niels E. Skakkebaek Section VI. Glucose Homeostasis Chapter 26 Hypoglycemia in Infants and Children Agneta Sunehag and Morey W. Haymond Chapter 27 Genetics of Type 1 Diabetes Alba Morales, Jin-Xiong She, and Desmond Schatz
