Extravasation of cytotoxic drugs can lead to serious complications during tumour therapy. This volume is intended as an aid to assess the situation quickly and conclusively should this emergency occur. The substance specific section of the book provides detailed instructions for how to deal with 49 cytotoxic agents so that targeted measures can be started at once. The general section provides comprehensive information on prevention, general measures to be taken in case of extravasation, specific antidotes, and documentation. For support during everyday clinical practice, the book is accompanied by a template for an extravasation kit, tables, documentation sheets, and patient information. The book is the outcome of a consensus of an interdisciplinary working group that has collected and systematically reviewed all published literature on the topic. The practical instructions are accompanied by a review of the literature to enable readers to study source materials via the original published studies.
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Contents: Problem outline Literature search methods General part: Introduction Predisposition and prevention Clinic Measures Extravasation kit Surgical Intervention Aftercare Documentation References Substance specific part: / Amsacrine / Asparaginase / Bendamustine / Bleomycin / Busulfan / Carboplatin / Carmustine / Cisplatin / Cladribine / Cyclophosphamide / Cytarabine / Dacarbazine / Dactinomycin / Daunorubicin / Daunorubicin liposomal / Docetaxel / Doxorubicin / Doxorubicin liposomal / Epirubicin / Estramustine / Etoposide / Etoposidphosphate / Fludarabine / 5-Fluorouracil / Fotemustin / Gemcitabine / Idarubicin / Ifosfamide / Irinotecan / Melphalan / Methotrexate / Mitomycin C / Mitoxantrone / Nimustine / Oxaliplatin / Paclitaxel / Pegaspargase / Pentostatin / Raltitrexed / Streptozocin / Teniposide / Thiotepa / Topotecan / Treosulfan / Trimetrexate / Vinblastine / Vincristine / Vindesine / Vinorelbine
