This text aids practitioners who seek to diagnose, treat and manage patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) more effectively. It discusses pulmonary gas exchange, muscle function and breathing, water/electrolyte imbalances and end-stage disease.
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Definitions, Nikos Siafakas and Nicholas Anthonisen; epidemiology of AECOPD, J. Vestbo; effect of AECOPD on the natural history and lung function, Nicholas Anthonisen, E. Lampiri, E. Argiana and S. Schiza; economic burden of AECOPD, S. Ramsey; pathophysiology of AECOPD, W. MacNee; pathology of AECOPD, P. Jeffery, M. Saetta and J. Zhu; biomarkers of AECOPD, R. Stockley; AECOPD - a systemic disease? E. Wouters; causes of AECOPD, W. Wedzicha; symptoms - signs of AECOPD, Dimitris Georgopoulos, E. Kondili and Nicholas Anthonisen; pulmonary gas exchange in AECOPD, Frederico P. Gomez and Roberto Rodriguez-Roison; radiology of AECOPD, K. Malagari and Voloudaki; assessment of severity of AECOPD, S. Rennard and C. Piquette; heart-lung interaction, Zoheir Bshouty; muscle function (and respiratory) in AECOPD, M. Decramer, T. Troosters and R. Gosselink; water/electrolyte imbalances in AECOPD, L. Fabbri; metabolism/nutrition in AECOPD, A. Schols; end-stage disease and AECOPD, B. Celli; sleep and AECOPD, W. McNicholas; antibiotics, Nicholas Anthonisen and Nikos Siafakas; bronchodilators, Nicholas Anthonisen; steroids, D. Niewoehner and K.L. Rice; oxygen, Nikos Siafakas and I. Mitrouska; others, Nikos Siafakas, N. Tzanakis and Eva Papadopouli; non-invasive ventilation, M. Elliot; invasive ventilation, Dimitris Georgopoulos and A. Rossi; weaning from the ventilator, A. Jubran; rehabilitation during AECOPD, N. Ambrossino and R. Porta; home management of AECOPD, J. Roca; hospital management of AECOPD, A. Agusti, E. Sala and M. Carrera; AECOPD as outcome of therapeutical interventions, Nikos Siafakas, J. Kottakis and M. Froudarakis; future research, P. Barnes.
