The Children's Hospital Oakland Hematology/Oncology Handbook

INTRODUCTION Chapter 1 - Objectives Resident Responsibilities ANEMIA Chapter 2 - Evaluation of Anemia Table 1 Normal RBC Values Table 2 Diagnostic Approach Table 3 History Table 4 Physical Exam Table 5 Evaluation of Iron Deficiency Oral Iron Challenge Parenteral Iron Erythropoietin Algorithm 1 Approach to Child with Anemia Algorithm 2 Diagnostic Approach to the Child with Microcytic Anemia Algorithm 3 Approach to the Newborn with Anemia Chapter 3 - Helolytic Anemia Algorithm 4 Approach to the Child with Hemolytic Anemia Chapter 4 - Sickle Cell Disease Fever and Infection Algorithm 5 Fever in a Child with Sickle Cell Disease Vaso-Occulusive Episodes Pain Management: Outpatient Inpatient Acute Chest Syndrome Algorithm 6 Sickle Cell Disease with Acute Pulmonary Infiltrate Priapism Stroke Splenic Sequestration Aplastic Crisis Avascular Necrosis Retinopathy/Hyphema Hyperbilirubinemia Peri-Operative Care Table 6 Immunization Recommendations Chapter 5 - Thalassemia Table 7 Classification of the Thalassemias Alpha Thalassemia Table 8 Alpha Thalassemia Syndromes Beta Thalassemia Table 9 Summary of Common Thalassmia Syndromes Neonatal Screening Management of Chronically Transfused Patients TRANSFUSION THERAPY Chapter 6 - Blood Products Red Blood Cells Sickle Cell Disease Oncology Platelets Granulocytes Plasma Preparation of Blood Products Chapter 7 - Transfusion Reactions Table 10 Drugs used in the Treatment of Nonhemolytic Transfusions Reactions Chapter 8 - Chelation Therapy Desferal Desensitization Protocol THE CHILD WITH A BLEEDING DISORDER Chapter 9 - Initial Evaluation Table 11 Obtaining a Bleeding History Table 12 Interpretation of Laboratory Studies Algorithm 7 Laboratory Evaluation of the Bleeding Child Chapter 10 - Inherited Bleeding Disorders von Wilebrand's Disease Factor VIII Deficiency Factor IX Deficiency and Other Rare Coagulation Deficiencies Chapter 11 - Management of Acute Hemorrhage Treatment of vWB Disease and Hemophelia Factor Administrative Instructions THE CHILD WITH THROMBOSIS Chapter 12 - Evaluation of the Child with Thrombosis Low Molecular Weight Heparin Therapy Table 13 Age-Dependent Dose of Enoxaparin NEUTROPENIA Chapter 13 - Neutropenia Algorithm 8 Approach to the Child with Neutropenia THROMBOCYTOPENIA Chapter 14 - Immune-Mediated Thrombocytopenia Neonatal Alloimmune Thrombocytopenia Table 14 Differential Diagnosis of Thrombocytopenia Algorithm 9.1 Approach to the Child with Thrombocytopenia Algorithm 9.2 Approach to the Child with Isolated Thrombocytopenia Algorithm 9.3 Approach to the Child with Thrombocytopenia/Anemia Chapter 15 - Non-Immune Mediated Thrombocytopenia Decreased Platelet Production THE CHILD WITH A MALIGNANCY Chapter 16 - Presentation and Initial Evaluation Table 15 Common Chief Complaints Table 16 Presenting Signs and Symptoms Table 17 Indications for Head CT with Headache Evaluation of the Child with Suspected Leukemia Evaluation of the Child with an Abdominal Mass Chapter 17 - Supportive Care General Measures/Prophlaxis Table 18 Ondansetron (Zofran) Dosing Guidelines Table 19 Immunization of the Children with Cancer Table 20 Passive Immunization of the Children with Cancer Table 21 A Quick Guide to Common Chemotherapy Drugs Guidelines for use of G-CSF Chills and Fever After a Broviac or Mediport Flush Guidelines for Clearing Obstructed Central Venous Catheters Chapter 18 - Fever and Neutropenia Algorithm 10 Evaluation of the Child with Fever and Neutropenia Chapter 19 - Oncologic Emergencies Superior Vena Cava Syndrome Abdominal Emergencies/Typhlitis Hyperleukocytosis Tumor Lysis Syndrome Chapter 20 - Guide to Oncologic Procedures IT Chemotherapy Intra-Ommaya Chemotherpay Bone Marrow Aspirate and Biopsy Chemotherpay (per PIV) APPENDIX Formulary INDEX