Although the incidence of coronary heart disease is falling, its major complication, heart failure, is increasing in frequency. All health care practitioners will encounter patients with heart failure, presenting either acutely or in need of chronic heart failure management. However with recent advances in medical therapy, the prognosis of the condition has improved dramatically so that whereas once heart failure was a pre-terminal diagnosis, now for many it is treatable. Taking the reader from an understanding of the basic mechanisms of heart failure through to an appreciation of the complexities of heart failure management and the remarkable improvements possible with good treatment, this definitive textbook is written by internationally renowned leaders in their field and comprehensively covers all aspects necessary to manage a patient with heart failure. In full colour throughout, containing over 300 illustrations, and supported by detailed referencing from the huge evidence base that has developed over the last two decades, Oxford Textbook of Heart Failure also includes extensive chapters on common co-morbidities, and will be essential reading for consultant cardiologists and those in training, general physicians and those caring of the elderly, cardiothoracic surgeons, primary care doctors, pharmacists, and specialist nurses. The printed edition is complemented by 6 months free access to an online version (also available for separate purchase on subscription basis), allowing users to search the text, and download the figures for use in PowerPoint presentations.
WHAT IS HEART FAILURE? ; 1. What is heart failure? ; 2. Heart failure syndromes ; EPIDEMIOLOGY ; 3. The epidemiology of heart failure ; THE AETIOLOGY OF HEART FAILURE ; 4. The classical causes of heart failure ; 5. The genetics of heart failure ; 6. Metabolic heart failure ; 7. Aetiology of congenital heart disease ; 8. Infective and infiltrative causes of heart failure ; 9. Iatrogenic heart failure ; PATHOPHYSIOLOGY OF HEART FAILURE: CELLULAR AND MOLECULAR CHANGES ; 10. Intracellular calcium handling in heart failure ; 11. Myocardial energetics ; 12. The failing cardiomyocyte ; PATHOPHYSIOLOGY OF HEART FAILURE: SYSTOLIC DYSFUNCTION ; 13. The pathophysiology of heart failure ; NEUROHORMONAL ADAPTATIONS ; 14. Cardiac natriuretic peptides and heart failure ; 15. Vasopressin ; 16. Cytokines and infl ammatory markers ; THE DIAGNOSIS OF HEART FAILURE ; 17. Diagnosing heart failure ; NONINVASIVE INVESTIGATION ; 18. Basic investigation of heart failure ; 19. Echocardiography ; 20. Nuclear medicine in heart failure ; 21. Heart failure imaged by cardiac magnetic resonance imaging ; 22. CT imaging techniques ; 23. Metabolic exercise testing in chronic heart failure ; INVASIVE INVESTIGATION ; 24. Invasive investigation ; PROGNOSTICATION ; 25. Prognostication ; COMORBIDITIES ; 26. Diastolic heart failure ; 27. Right heart failure ; 28. The patient with heart failure and anaemia ; 29. The patient with heart failure and renal dysfunction ; 30. The patient with heart failure and chronic lung disease ; 31. Pulmonary hypertension in left heart disease ; 32. Heart failure and diabetes mellitus ; 33. The patient with valvular heart disease and heart failure ; 34. The patient with heart failure and sleep-disordered breathing ; 35. Heart failure and arthritis ; 36. The patient with heart failure and arrhythmias ; MEDICAL THERAPY FOR CHRONIC HEART FAILURE ; 37. Angiotensin converting enzyme inhibitors and vasodilators ; 38. ? -Adrenoreceptor antagonists and heart failure ; 39. Aldosterone antagonists ; 40. Angiotensin receptor blockers ; 41. Therapeutic control of fl uid balance in chronic heart failure ; 42. Digoxin ; 43. Antithrombotic agents ; MEDICAL THERAPY FOR ACUTE HEART FAILURE ; 44. Inotropes, pressors, and vasodilators ; NONPHARMACOLOGICAL MANAGEMENT ; 45. Cardiac rehabilitation and chronic heart failure ; 46. Nonpharmacological management ; DEVICE THERAPY FOR HEART FAILURE ; 47. Implantable cardioverter-defi brillators in heart failure ; 48. Cardiac resynchronization therapy ; SURGICAL THERAPY FOR HEART FAILURE ; 49. Heart transplantation ; 50. Revascularization and remodelling surgery ; 51. Ventricular assist devices, including intra-aortic balloon pumps ; 52. Mitral valve surgery in heart failure ; VENTILATORY STRATEGIES IN HEART FAILURE ; 53. Ventilatory strategies in acute heart failure ; DISEASE MANAGEMENT ; 54. Multidisciplinary heart failure management programmes ; 55. End of life ; 56. Monitoring ; FUTURE THERAPIES ; 57. The future
