Malattie vascolari del S.N.C

New and groundbreaking therapeutic options for the critical care of patients with cerebrovascular disease have improved patient management, minimized morbidity, reduced in-patient care, improved quality of life, and had a positive economic impact on health service provision. This volume integrates these approaches and suggests the best therapy option for all cerebrovascular conditions. The early chapters of the book focus on monitoring techniques and interventions. Subsequent sections address the critical care of a wide range of cerebrovascular diseases: ischemic stroke, intracranial hemorrhage, subarachnoid hemorrhage, arteriovenous malformations, cerebral venous thrombosis and traumatic injury. The editors and authors are internationally recognized experts in their field, and the text is supplemented by tables and illustrations to demonstrate important clinical findings. This book will meet the needs of stroke physicians, neurologists, neurosurgeons, neurointensivists and interventional neuroradiologists seeking to maximize positive outcomes for their patients.

Seconda causa di morte della popolazione e prima causa di invalidità, l'ictus cerebrale è oggi un vero problema sociale oltre che medico. La prevenzione è certo il primo pilastro per arginarne le conseguenze. Al tempo stesso gli avanzamenti della ricerca hanno messo a disposizione strategie terapeutiche efficaci nella fase acuta che permettono di ottenere un recupero neurologico in più del 50% dei casi. In questo volume: le cause, i fattori di rischio, la prevenzione, i nuovi modelli assistenziali, come le Stroke Unit, e le novità terapeutiche insieme a quelle attese nel futuro.

Designed for use by busy professionals who need quick answers, this revised and updated second edition of The Stroke Book is a concise and practical reference for anyone involved in managing critically ill cerebrovascular patients. * Covers a wide range of common conditions such as ischemic and hemorrhagic strokes, subarachnoid hemorrhages and intracranial aneurysms * Provides focused protocols for assessing and treating stroke patients in the emergency room, intensive care unit or general hospital setting * A new chapter summarizes key clinical trials for stroke therapies * User-friendly format * Packed with algorithms, tables and summary boxes for immediate access to key information * A color plate section illustrates key pathology and diagnostic imaging Written by experienced contributors from leading stroke centers, this is an essential companion for navigating stroke-related clinical situations successfully and making informed decisions about treatment.

Handbook of Clinical Nutrition and Stroke is a comprehensive reference on nutrition for the multidisciplinary team caring for stroke patients. Targeting physicians, nurse practitioners, clinical dietitians, and advanced allied health and medical students, this volume provides an introduction on the different types of stroke, associated risk factors, and uniquely featured global perspectives on stroke. In addition to discussing stroke risk factors, the book expands upon treatment and management from the acute care setting through rehabilitation, captures the lifespan of patients affected by stroke, and discusses the progression of the nutrition care plan. Containing the most up-to-date, evidence based information currently available, Handbook of Clinical Nutrition and Stroke is a valuable resource for clinicians working with the stroke population.

This book considers various topics regarding stroke, including bedside evaluation of the acute stroke patient; neurovascular imaging of the acute stroke patient; treatment of acute ischemic stroke; treatment of hemorrhagic stroke; prevention and management of post-stroke complications; diagnosis of stroke mechanism and secondary stroke prevention; post-stroke recovery; and considerations for very elderly and severely affected stroke patients. It is essential reading for neurologists and cardiologists.

The ever-improving emergency care of those who have suffered serious cerebrovascular disease has shifted the treatment objective towards helping sufferers regain independence - meaning that there is an increased need to understand, manage and treat the residual deficits. The Behavioral and Cognitive Neurology of Stroke focuses on the diagnosis and management of behavioral and cognitive problems in patients with cerebrovascular disease. Written to be practical for clinical use, the book contains diagnosis and management strategies for all disorders observed in stroke patients, including acute and later problems, and aiming to minimize long-term disability. All important information related to each disorder is summarized in key-point tables. Fully updated throughout and containing five new chapters, this new edition brings the book up to date with the major advances of the last five years. This book will be of value to all clinicians caring for stroke patients, neuroscientists, neuropsychologists, neurorehabilitationists and a wide range of therapists.

Stroke remains one of the main causes of death and disability worldwide. While effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.

Invaluable for all members of the stroke team, this expertly written book compiles the full range of diagnostic and interventional therapeutic techniques for acute stroke now in use in modern clinical settings throughout the world. From advanced neuroimaging studies to state-of-the art endovascular therapies, it covers the materials, instruments, devices, procedures, and strategies that lead to optimal results, and most benefit the patient, during this time-critical event. Special Features: * An interdisciplinary approach* Provides detailed how-to descriptions of all endovascular stroke treatment techniques, periprocedural monitoring, and instrumentation, with a focus on implementing these methods in everyday practice* Logically organized in didactically structured chapters on diagnosis and treatment, with sections on acute ischemic stroke, acute venous occlusions, and supra-aortic extra- and intracranial stenoses, including their etiology, pathogenesis, symptoms, imaging studies, and recommended therapies for each condition* Written by a team of renowned international specialists, who provide advice, recommendations, and practical guidelines in every chapter* Discusses the stents, retrievers, filters, and balloon systems in use today * Includes nearly 300 key images taken with the latest generation of imaging equipment * Shares helpful clinical insights in sidebar notes, cautions, tips and advice, possible complications, sources of error, and useful chapter summaries/conclusions For all neuroradiologists, radiologists, neurosurgeons, and neurologists who need concise, clinically relevant information on front-line interventional techniques for stroke treatment and prevention, this book is essential. It reviews all current methods, rates their efficacies, and makes progress toward a uniformity of protocols that can be applied in all practices managing stroke patients.

Over the past ten years, there has been an increasing recognition that syndromes of frontotemporal dysfunction (FTD) are a common occurrence in patients with amyotrophic lateral sclerosis (ALS). Such syndromes may be present in as many as 60% of patients with ALS. Conversely, the occurrence of motor neuron dysfunction in patients with clinically pure frontotemporal dementia is increasingly recognized. This suggests that to some extent there are overlapping syndromes in which both ALS and FTD occur within the same individual. This volume summarizes the advances in our understanding of these two disorders, as well as the potential relationship between the two. Key topics include advances in our ability to clinically describe the frontotemporal syndromes, preclinical detection, neuroimaging, and genetics. The exploding field of new markers in neuropathology is examined, as is the role of new genetic mutations in DNA/RNA transport systems. This book is the essential reference text for this topic, and will be of interest to neurologists and neurological trainees with a clinical or research interest in the FTDs or ALS, neuropsychologists, neuropathologists, and researchers.

Fully revised and updated, the Handbook serves as a practical guide to endovascular methods and as a concise reference for neurovascular anatomy and published data about cerebrovascular disease from a neurointerventionalist's perspective. Divided into three parts, the book covers: Fundamentals of neurovascular anatomy and basic angiographic techniques; Interventional Techniques and endovascular methods, along with useful device information and tips and tricks for daily practice; Specific Disease States, with essential clinical information about commonly encountered conditions. New features in the 2nd Edition include: Global Gems that illuminate aspects of the field outside the United States; Angio-anatomic and angio-pathologic image correlates; Newly released clinical study results influencing neurointerventional practice; Information on emerging technologies in this rapidly advancing field. The Handbook is a vital resource for all clinicians involved in neurointerventional practice, including radiologists, neurosurgeons, neurologists, cardiologists, and vascular surgeons.

Progressive multiple sclerosis places huge burdens on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws together the field into a single accessible, clinically focused text. Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated and specific pathophysiological mechanisms. The basic science of axonal degeneration and clinical understanding of progressive multiple sclerosis is discussed in the context of emerging and future therapies for disease progression as well as discussion of how trials might be conducted for progressive multiple sclerosis and an overview of biomarkers for the disease. Existing symptomatic therapies for progressive multiple sclerosis are discussed in detail.

The first two editions of Stroke Syndromes were widely welcomed as authoritative reference works in the assessment and diagnosis of stroke. This revised and updated third edition remains the definitive guide to patterns and syndromes in stroke. A comprehensive survey of all types of neurological, neurophysiological and other clinical dysfunction due to stroke. The book contains descriptions of clinical problems encountered in stroke patients and their differential diagnosis, enhancing pattern recognition and enabling clinicians to differentiate between possible locations on the basis of symptoms and signs. The companion volume Uncommon Causes of Stroke completes this highly authoritative reference work which clinicians in neurology will find essential to the understanding and diagnosis of stroke.

Clinical evidence clearly demonstrates that physical therapeutic measures begun as soon as possible after a stroke, often within 24 to 48 hours, greatly increase everyday competence and quality of life. Physical Therapy for the Stroke Patient: Early Stage Rehabilitation covers all the issues that physical therapists must deal with in this critical period: assessment of patients' abilities; care during the acute phase; early mobilization; effects of medication; risk factors; ethical questions; and much more. It provides complete guidelines on how to examine and treat the patient, the dosage of physical therapy required, and the key differences between early and late stage rehabilitation after stroke. Special Features: * Information-packed chapter on Optimizing Functional Motor Recovery after Stroke, written by J. Carr and R. Shepherd, pioneers in the field and the first to correlate motor learning and stroke recovery* Case studies throughout the book offering direct, hands-on examples of evaluation and treatment methods* Nearly 150 color photographs demonstrating step-by-step physical therapy techniques used in actual practice* Hundreds of references to the literature that support the evidence-based approach presented in the book For all physical and occupational therapists who must answer the question, How much therapy will help my patient?, this book provides clear, well-informed answers. Not only will it increase your therapeutic skills and confidence, but it will also expand your knowledge of the medical issues and long-term outcomes for the post-stroke patients in your care.

The volume includes 75 papers which were presented at the Third International Conference on Intracerebral Hemorrhage, held in Rancho Mirage, California, in March 2010. The topics treated include animal models, pathophysiology of cerebral hemorrhage, experimental treatment for cerebral hemorrhage, cerebral hemorrhage clinical manifestations, prognosis of cerebral hemorrhage, and clinical management. The articles represent the recent advances in hemorrhagic brain injury research presented by highly respected laboratories around the world.

Endovascular intervention - using medication and devices introduced through catheters or microcatheters placed into the blood vessels through a percutaneous approach - has emerged as a relatively new minimally invasive approach to treat cerebrovascular disease and possibly intracranial neoplasms. This textbook provides a comprehensive review of principles pertinent to endovascular treatment of cerebrovascular diseases and intracranial tumors, with a detailed description of techniques for these procedures and periprocedural management strategies. Particular emphasis is placed on expert interpretation of the quality of evidence provided and implications for practice related to endovascular procedures. This will be essential reading for clinicians working in interventional neurology and cardiology, endovascular neurosurgery, vascular surgery and neuroradiology.

Stroke is the most common cause of adult disability and is of increasing importance within ageing populations. This brand new title in the ABC series covers the entire patient journey, from prevention through to long-term support. It includes primary prevention and management of risk factors for stroke and secondary prevention including pharmaceutical, lifestyle and surgical intervention. The general principles of stroke rehabilitation are also addressed as well as mobility, communication and psychological problems, as is stroke in younger people. It also covers long-term support for stroke survivors and their carers. This is an invaluable and practical guide to all aspects of stroke for both health care professionals and lay audiences. It is of particular relevance to general practitioners, junior doctors, nurses and therapists working with stroke patients and their carers, and to people with stroke and their families.

Increasing evidence identifies the possibility of restoring function to the damaged brain via exogenous therapies. One major target for these advances is stroke, where most patients can be left with significant disability. Treatments have the potential to improve the victim's quality of life significantly and reduce the time and expense of rehabilitation. Brain Repair After Stroke reviews the biology of spontaneous brain repair after stroke in animal models and in humans. Detailed chapters cover the many forms of therapy being explored to promote brain repair and consider clinical trial issues in this context. This book provides a summary of the neurobiology of innate and treatment-induced repair mechanisms after hypoxia and reviews the state of the art for human therapeutics in relation to promoting behavioral recovery after stroke. Essential reading for stroke physicians, neurologists, rehabilitation physicians and neuropsychologists.