Epidemiologia

"I think this is an excellent book-I recommend it to anyone involved in molecular epidemiology...The 26 chapters are written by topic specialists, in an explanatory, east to read style." -BTS Newsletter, Summer 2009 "This text provides an accessible and useful handbook for the epidemiologist who wants to survey the field, to become better informed, to look at recent developments and get some background on these or simply to appreciate further the relatively rapid changes in informatic and analytical technologies which increasingly will serve and underpin future epidemiological studies. One of the strengths in this book is the extensive array of practical illustrative examples, and it would also in my opinion have useful potential as a teaching text." -American Journal of Human Biology, March 2009 With the sequencing of the human genome and the mapping of millions of single nucleotide polymorphisms, epidemiology has moved into the molecular domain. Scientists can now use molecular markers to track disease-associated genes in populations, enabling them to study complex chronic diseases that might result from the weak interactions of many genes with the environment. Use of these laboratory generated biomarker data and an understanding of disease mechanisms are increasingly important in elucidating disease aetiology. Molecular Epidemiology of Disease crosses the disciplinary boundaries between laboratory scientists, epidemiologists, clinical researchers and biostatisticians and is accessible to all these relevant research communities in focusing on practical issues of application, rather than reviews of current areas of research. * Covers categories of biomarkers of exposure, susceptibility and disease* Includes chapters on novel technologies: genomics, transcriptomics, proteomics and metabonomics, which are increasingly finding application in population studies* Emphasizes new statistical and bioinformatics approaches necessitated by the large data sets generated using these new methodologies* Demonstrates the potential applications of laboratory techniques in tackling epidemiological problems while considering their limitations, including the sources of uncertainty and inaccuracy* Discusses issues such as reliability (compared to traditional epidemiological methods) and the timing of exposure* Explores practical elements of conducting population studies, including biological repositories and ethics Molecular Epidemiology of Disease provides an easy-to-use, clearly presented handbook that allows epidemiologists to understand the specifics of research involving biomarkers, and laboratory scientists to understand the main issues of epidemiological study design and analysis. It also provides a useful tool for courses on molecular epidemiology, using many examples from population studies to illustrate key concepts and principles.

"Lecture Notes: Epidemiology and Public Health Medicine" new edition, is a core text that covers the basics of epidemiology, preventive medicine, public health, and the organisation of medical care. The book is divided into three parts: Part 1 Written to provide background and detailed information on epidemiology and public health medicine. Casue and risk factors are discussed along with examples of theory and practice. The different types of epidemiological study design, sources of information and demographical data and studies are included. Part 2 Evidence-based medicine is covered along with general principles on epidemiology. Promoting and educating on the control and immunisation procedures are dicsussed, with empahsis on environmental health and preventative methods and screening are topics highlighted.Part 3 Historical cases and principles are reviewed. The effects on epidemiology and public health is dicussed in relation to the National Health Service, and targets and evaluation procedures are covered. Lecture Notes: "Epidemiology and Public Health Medicine" is aimed at setting the basic medical science into a global and clinical setting. The book will appeal to all medical students and practising doctors who want to make clinical decisions based on sound evidence. Public health Nurses may also find this book as a useful resource too. Review quotations from the previous edition: "makes the best job possible of explaining the seemingly impenetrable jungle of epidemiology" - "Scope Magazine".

Field epidemiology involves the application of epidemiologic methods to unexpected health problems when a rapid on-site investigation is necessary for timely intervention. Based on decades of experience in both infectious and non-infectious diseases at the Centers for Disease Control and Prevention, this book describes in simple and practical terms the distinct approach, tasks, and actions needed for successful field investigations. Guidance is given on such issues as how to perform surveillance, manage and execute field investigations, collect and analyze data, perform surveys, adapt a personal computer for field use, and communicate the findings. Specific advice is also given on such subjects as dealing with the media; investigations in healthcare, day-care, and international settings; and the legal aspects of field studies. An entire chapter covers the proper collection, handling, and testing of infectious and non-infectious agents in the field. In the Second Edition, four new chapters cover many unique aspects of field studies in the workplace, after natural disasters, in preparation for and response to possible bioterrorist attacks, and by state and local health departments. Finally, an appendix describes how to investigate a common source food-borne epidemic. This text gives public health professionals and students a practical and complete reference to use in virtually any field investigation setting.

The basis for much of medical public health practice comes from epidemiological research. This text describes current statistical tools that are used to analyse the association between possible risk factors and the actual risk of disease. Beginning with a broad conceptual framework on the disease process, it describes commonly used techniques for analysing proportions and disease rates. These are then extended to model fitting, and the common threads of logic that bind the two analytic strategies together are revealed. Each chapter provides a descriptive rationale for the method, a worked example using data from a published study, and an exercise that allows the reader to practice the technique. Each chapter also includes an appendix that provides further details on the theoretical underpinnings of the method. Among the topics covered are Mantel-Haenszel methods, rates, survival analysis, logistic regression, and generalised linear models. Methods for incorporating aspects of study design, such as matching, into the analysis are discussed, and guidance is given for determining the power or the sample size requirements of a study. This text will give readers a foundation in applied statistics and the concepts of model fitting to develop skills in the analysis of epidemiological data.

Cancer screening programmes have become routine practice throughout the developed world -- aiming to detect the presence of the disease prior to the manifestation of symptoms, and to increase the likelihood of successful treatment. Naturally, these programmes require regular monitoring to ensure that screening quality is maintained, and to advance the early-warning system as much as possible. Quantitative Methods for the Evaluation of Cancer Screening is a professional title designed to provide the researchers of these screening programmes with up-to-date methods and tools for improving evaluation. The book presents an introduction to cancer screening and to the methods that are employed for its monitoring, followed by an in-depth account of the more complicated modelling approaches. Each chapter is written by an international expert in the field, and imparts practical specialist information that the reader can apply to the evaluation of their own programmes. Case studies illustrate the methods in practice and provide further illumination of the fields of breast, cervix, large bowel, and neuroblastoma screening.

Written by renowned epidemiologists and public health experts, this unique text provides complete, concise coverage of epidemiology, biostatistics, preventive medicine, and public health in clear, easy-to-understand terms. One convenient volume delivers must-know content in four complex areas-information that’s sure to be covered in today’s classrooms and on USMLE exams-presented with a clinical focus and real-life medical examples throughout. Depth of coverage, concise writing style, outstanding online review questions, a clinical emphasis … these features and more make Jekel's your go-to resource for learning, study, and review. Focuses on clinical problem solving and decision making using epidemiologic concepts and examples Contains more clinical cases throughout, including global examples. Offers expanded coverage of the impact of big data and precision medicine, as well as an updated and reorganized biostatistics section Features quick-reference boxes that showcase key concepts and calculations, and dynamic illustrations that facilitate learning using a highly visual approach Provides almost 300 multiple-choice chapter review questions and answers in print with additional questions and more online at Student Consult Aligns content to board blueprints for the USMLE as well as the three specialties certified by the American Board of Preventive Medicine: Occupational Medicine, and Public Health & General Preventive Medicine-and is recommended by the ABPM as a top review source for its core specialty examination Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all the text, figures, and references from the book on a variety of devices Evolve Instructor site, with an image and table bank as well as chapter overviews as PowerPoints, is available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com