Demenze

This thoughtful new work begins by asking the question 'what is normal in cognitive and pathological ageing?' The clinician's experience of dementia and mild cognitive impairment suggests that these conditions present in a variety of forms and progress at different rates, with a spectrum of disability ranging from a barely perceptible loss of mental acuity to the severe debilitation of advanced Alzheimer's disease. This atlas utilises diagnostic imaging, histopathological findings, schematic diagrams and other graphics to illustrate the symptom profiles, aetiology, and epidemiology of the more common dementias. The authors present comparisons of Alzheimer's and Lewy body disease, frontal temporal and vascular dementias and other dementing illnesses, to illustrate the problems inherent in distinguishing between them, and in making a diagnosis.

Aims to provide a user-friendly review of contemporary knowledge and thinking on dementia. This book contains chapters on diagnosis, clinical features, assessment, management of cognitive impairment and non-cognitive dysfunctions, nursing care, community care, as well as reviews of global perspectives and research on dementia.

Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.

There are over one million people in the UK alone suffering from some form of dementia. Cures for dementia are still a long way off, but if diagnosed early enough there are treatments available which delay the onset of the disease and provide a better quality of life. The key to treatment is early diagnosis, and it is here that GPs and family care practitioners need help. This book, written by a neurologist and a psychiatrist in the Q and A format of the series, covers all types of dementia, including Alzheimer's Disease, and will help GPs and other family care practitioners provide early diagnosis and treatment to the millions of patients suffering from dementia. It also includes useful information on services and sources of further help for dementia sufferers and their carers.

This new book in the Practical Guides in Psychiatry series focuses on the assessment and clinical management of the various forms of dementia and associated psychiatric conditions. In an engaging writing style with many clinical vignettes, Dr. Agronin describes the patient and caregiver interview, the diagnostic tests used in the workup, the types of dementia, the psychiatric conditions associated with dementia, and the pharmacological and behavioral treatments available. He also offers advice on social, ethical, and legal concerns and on support of caregivers. Psychiatry residents especially will find Dementia invaluable in their training. "Key points and quick-reference tables complement the text. Appendices include prescribing information on psychotropic drugs and patient/caregiver education handouts

Vascular dementia, caused by multiple small strokes, is the second commonest cause of dementia behind Alzheimer's disease. In recent years there has been a radical reappraisal of the concept of vascular dementia and a move away from an Alzheimer-based diagnostic paradigm towards one more appropriately tailored for vascular disease. Vascular Cognitive Impairment presents a new definition for this class of cerebrovascular process with an emphasis on early detection, prompt treatment and the prevention of disease progression. Vascular Cognitive Impairment: Preventable Dementia presents an overview of the current state of our knowledge in this field. It reviews the historical background, prevalence, risk factors and economic consequences of the condition. In addition, the book summarises our knowledge of the pathological process, describing insight derived from genetic and imaging studies, before examining opportunities for early diagnosis, prevention and the options for management, both now, and as a result of ongoing clinical trials. With contributions from an expert team of international contributors, this book provides a comprehensive summary of the state-of-the-art in this field, providing a framework for a new understanding of a complex, disabling but Preventable condition.

Confusion. Fear. Isolation. This is the human experience of dementing illness, and it is at the heart of this practical, informative volume by a broad range of clinically grounded experts. This book is designed to meet the needs of clinicians dealing with persons with dementing illness and to serve as an introduction to the pathophysiology of dementing illness and a resource for clinical investigators. The giant strides in dementia research since the publication of the first edition in 1991 have generated optimism that we will soon be able to delay onset and even prevent these diseases that devastate both patients and caregivers. This third edition has been revised, updated, and expanded to cover changes in the classification, management and treatment of dementing illnesses and to give a more extensive account of basic and clinical research findings. At the same time, this remarkable volume indicates the interaction of the patient's personality, the caregiver, and the environment with the pathophysiology of dementing illnesses that creates the variety of symptoms accompanying these illnesses and impacting their treatment. Like the second edition, this third edition has three sections, flowing from diagnosis through management/treatment to research. New to this edition are * A world-class presentation on the molecular and genetic basis of Alzheimer's disease* A beautifully illustrated chapter on contemporary neuroimaging* Discussions of mild cognitive impairment, the frontotemporal dementias, and the dementias associated with Lewy bodies This third edition is exceptionally valuable for addressing the day-to-day challenges of dealing effectively and humanely with persons with dementing illness. Case examples are used in the chapters on psychological/behavioral and drug management to indicate practical approaches to maintaining patients at their optimal level of function. Unlike similar texts, this volume also reviews legal and ethical issues in the care of persons with dementing illness and shows how clinicians and caregivers how to mobilize community resources. Extensive reference lists round out each chapter. The book concludes with 11 assessment guides and rating scales and an index. Now more than ever, there is hope that advances in understanding dementing illnesses such as Alzheimer's disease will lead to their effective treatment, and ultimately to their prevention. Until then, clinicians, families, and society will continue to be faced with the challenges posed by these illnesses -- making this book a "must read" for physicians and other health care professionals, whether in training, in practice, or engaged in clinical research.