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Libri di Riccardo Lencioni

Advances in Diagnostic Imaging

The Value of Contrast-enhanced Ultrasound for Liver

Jean-Michel Correas, Riccardo Lencioni
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editore: Springer Verlag

pagine: 64

In recent years, the imaging-based diagnosis of mass liver lesions has become increasingly complex due to the number and morphological variability of lesions that modern imaging techniques are currently able to display. If the sensitivity in detection has greatly increased, characterisation has remained difficult and represents a critical challenge for the clinician. The availability of blood-pool contrast agents for ultrasound (US), in particular second-generation US contrast agents based on perfluorocarbon- or sulfur-hexafluoride-filled microbubbles, and the development of contrast-specific software and technologies have opened up new perspectives both for the immediate characterisation of any mass lesion detected in the liver and for increasing the sensitivity of US in the detection of liver metastases. Taking into account the great impact of this new technology on clinical practice, the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) organised, in January 2004, in Rotterdam, a consensus meeting of experts in order to develop guidelines for the use of US contrast agents in the diagnosis of liver diseases . These guidelines, as well as discussions of further advances in the clinical application of contrast-enhanced harmonic US are presented in this book by an internationally renowned group of experts. The book represents provides an important starting point for clinical implementation of this new diagnostic procedure.
51,99 49,39

Magnetic Resonance Imaging in Liver Disease

Technical Approach, Diagnostic Imaging of Liver Neoplasms, Focus on a New Superparamagnetic Contrast Agent

Ranate M Hammerstingl, Riccardo Lencioni
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editore: Thieme Publishing Group

pagine: 312

Early and accurate diagnosis forms the basis for appropriate and successful treatment of patients with liver tumours. Pre- and post-therapeutic imaging techniques, such as ultrasound, CT, and MRI imaging - unenhanced as well as contrast-enhanced - are used to detect liver tumours and differentiate between malignant and benign lesions. Once a lesion is detected, the ratio of involved versus non-involved liver segments must be assessed. Preoperative imaging in patients with hepatocellular carcinomas and liver metastases directly influences further therapeutic considerations, e.g., resection, liver transplantation, or regional therapeutic procedures, such as transcatheter arterial infusion therapy for arterial embolization, percutaneous ethanol instillation, chemotherapy, laser or radio frequency. Iron oxide-enhanced MRI as a non-invasive technique provides a high preoperative diagnostic efficacy for diagnosis of liver disorders. Superparamagnetic iron oxide particles are absorbed by the Kupffer cells of normal liver parenchyma and by tumors consisting of RES. This results in a signal change in MR images and various types of characteristic features of tissues. Resovist is a new iron oxide contrast agent that can be applied via intravenous bolus injection. It allows dynamic iron oxide-enhanced imaging for the first time. In this book, both the basic principles and the latest results in the use of contrast-enhanced MRI of the liver are presented. This work will allow the reader to understand and use superparamagnetic contrast agents for evaluating various diseases of the liver.
99,00 94,05

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