Libri di Michael T. Lotze
Biografia e opere di Michael T. Lotze
Natural Killer Cells
Basic Science and Clinical Application
Angus W. Thomson , Michael T. Lotze
editore: Academic Press Inc
pagine: 660
Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, such as herpes viruses and influenza viruses. The book also explains the primary functions of killer cells, and it discusses how these cells help recognize damaged tissues, limit further damage to tissues, and regenerate damaged tissues. It discusses how these cells mature and develop, and it covers the different isolation, culture, and propagation methods of these cells. Furthermore, it focuses on the different killer cells that are present in various parts of the human body. The book concludes by explaining that natural killer cells are utilized for clinical therapy of malignancies, and that they have led to positive outcomes in the field of biology and medicine. - Provides a broad, detailed coverage of the biology and interactions of NK cells for students, fellows, scientists, and practitioners - Includes figures, histologic sections, and illustrations of the ontogeny of NK cells - Companion website includes full-color image database
Measuring Immunity
Basic Science and Clinical Practice
Angus W. Thomson , Michael T. Lotze
editore: Academic Press Inc
pagine: 736
Most of the diseases of modern mankind involve either acute or chronic inflammation. "Measuring Immunity" integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. "Measuring Immunity" is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. It defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity. It assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques. It includes basic science foundations as well as the approaches currently applied.
Cytokine Handbook
Angus W. Thomson , Michael T. Lotze
editore: Academic Press Inc
pagine: 1572
The fourth edition of "The Cytokine Handbook" provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. It covers all main cytokines and chemokines. It is up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome. The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters.
It includes major emphasis on clinical applications and is extensively illustrated with tables and figures.
Tumor Immunology
Molecularly Defined Antigens and Clinical Applications
Giorgio Parmiani , Michael T. Lotze
editore: Taylor & Francis Ltd
pagine: 224
Recent advances in immunology and molecular biology have resulted in new therapeutic approaches being generated and implemented in cancer clinics. The discovery of new antigens, mechanisms of antigen presentation, and interplay of cells involved in anti-tumor immunity have made the clinical control of some cancers more plausible than previously thought. An invaluable source for clinicians, researchers, and students, Tumor Immunology presents an introductory overview of the immunology of cancer including therapeutic approaches. Topics covered include the immune recognition of cancer-tumor antigens, humoral recognition of cancer, and the immunotherapy of cancer.
Dendritic Cells
Biology and Clinical Applications
Angus W. Thomson , Michael T. Lotze
editore: Academic Press Inc
pagine: 794
"Dendritic Cells, 2nd Edition" is the new edition of the extremely successful book published in 1998. With the volume of literature on dendritic cells doubling every year, it is almost impossible to keep up. This book provides the most up-to-date synthesis of the literature, written by the very best authors. It is essential reading for any scientist working in immunology, cell biology, infectious diseases, cancer, transplantation, genetic engineering, or the pharmaceutical/biotechnology industry. An entirely new section on DC biology is included in this edition. Also new to this edition are chapters on: Imaging; Interaction of dendritic cells with viruses; Dendritic cells and dendrikines, chemokines and the endothelium; Molecules expressed in dendritic cells; Role of dendritic cells in wound healing and atherosclerosis; Delivery of apoptotic bodies; Genetic engineering of dendritic cells; and practical aspects of clinical protocol development.
