Libri di Frederick Sachs

Cardiac Mechano-Electric Coupling and Arrhythmias offers a thoroughly reviewed compendium written by leading experts in the field on the mechanism and consequences of cardiac mechano-electrical coupling. Its coverage ranges from stretch-activated ion channels to mechanically induced arrhythmias and mechanical interventions for heart rhythm correction. Information is grouped into logical sections, from molecular mechanisms, to cell, tissue and whole organ responses, right through to patient-based observations and insight emerging from clinical trials. The information provided carefully highlights both consensus insight and current shortcomings in our understanding of cardiac mechano-electric coupling. The book has been thoroughly revised and expanded since publication of the first edition in 2005, extensively updated to reflect recent developments in the field, and now offers a more balanced view of mechano-electrical interactions in the heart and develops a more clinical focus. Written with the practising cardiologist and junior doctor in mind, it offers interesting new insight for the established physician with an interest in cardiac arrhythmogenesis and heart rhythm management.

Better understand the mechanisms of arrhythmia, cellular modifiers, and the clinical answers to these disorders! Written by internationally recognized leaders in the field, this groundbreaking resource reflects the state of the art in all aspects of mechanical heart function. Readers will find detailed discussions of mechanisms of feedback; effects on cellular electrophysiology; experimental manifestations; normal physiology; pathogenic mechanisms; therapeutic interventions; and, more.