Insights from the Rabbit Model
editore: American Society for Microbiology
Examines the pathogenesis of human pulmonary tuberculosis in all of its stages, with a primary focus on the rabbit model. * Reviews the interplay of delayed-type hypersensitivity and cell-mediated immunity, clearly showing how both are needed to control the growth of the tubercle bacillus and how antibodies contribute to these cellular immune responses. * Covers the histochemistry of macrophage activation; the roles of various cytokines; the effects of glucocorticoids, estrogens, thyroid hormones, and irradiation on the disease; and principles of immunization against tuberculosis, including vaccine development. * Focuses on areas of future research that could contribute to the knowledge, treatment, and control of this disease. * Serves as a resource for clinicians, public health investigators, and laboratory researchers in tuberculosis and immunology.