Now in its 10th edition, Sleisenger and Fordtran's Gastrointestinal and Liver Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of gastroenterology and hepatology. Overcome your most complex clinical challenges and make optimal use of the newest techniques, technologies, and treatments-with superb guidance from hundreds of world-renowned authorities. Meticulous updates throughout include the latest approaches and improvements in gastrointestinal and liver disease diagnosis and therapy as well as hundreds of images and 35 new procedural videos.
Section I. Biology of the Gastrointestinal Tract 1. Cellular Growth and Neoplasia 2. Mucosal Immunology and Inflammation 3. Enteric Microbiota 4. Gastrointestinal Hormones and Neurotransmitters Section II. Nutrition in Gastroenterology5. Nutritional Principles and Assessment of the Gastroenterology Patient 6. Nutritional Management 7. Obesity 8. Surgical and Endoscopic Treatment of Obesity 9. Feeding and Eating Disorders 10. Food Allergies Section III. Symptoms, Signs, and Biopsychosocial Issues11. Acute Abdominal Pain 12. Chronic Abdominal Pain 13. Symptoms of Esophageal Disease 14. Dyspepsia 15. Nausea and Vomiting 16. Diarrhea 17. Intestinal Gas 18. Fecal Incontinence 19. Constipation 20. Gastrointestinal Bleeding 21. Jaundice 22. Biopsychosocial Issues in Gastroenterology 23. Factitious Gastrointestinal Disease Section IV. Topics Involving Multiple Organs 24. Oral Disease and Oral-Cutaneous Manifestations of Gastrointestinal and Liver Disease 25. Diverticula of the Pharynx, Esophagus, Stomach, and Small Intestine 26. Abdominal Hernias and Gastric Volvulus 27. Foreign Bodies, Bezoars, and Caustic Injury 28. Abdominal Abscesses and Gastrointestinal Fistulas 29. Eosinophilic Disorders of the Gastrointestinal Tract 30. Protein-Losing Gastroenteropathy 31. Gastrointestinal Lymphomas 32. Gastrointestinal Stromal Tumors (GISTs) 33. Neuroendocrine Tumors 34. Gastrointestinal Consequences of Infection With Human Immunodeficiency Virus 35. Gastrointestinal and Hepatic Complications of Solid Organ and Hematopoietic Cell Transplantation 36. Gastrointestinal and Hepatic Manifestations of Systemic Diseases 37. Vascular Disorders of the Gastrointestinal Tract 38. Surgical Peritonitis and Other Diseases of the Peritoneum, Mesentery, Omentum, and Diaphragm 39. Gastrointestinal and Hepatic Disorders in the Pregnant Patient 40. Radiation Injury 41. Preparation for and Complications of GI Endoscopy Section V. Esophagus 42. Anatomy, Histology, Embryology, and Developmental Anomalies of the Esophagus 43. Esophageal Neuromuscular Function and Motility Disorders 44. Gastroesophageal Reflux Disease 45. Barrett's Esophagus 46. Esophageal Disorders Caused by Medications, Trauma, and Infection 47. Esophageal Tumors Section VI. Stomach and Duodenum 48. Anatomy, Histology, and Developmental Anomalies of the Stomach and Duodenum 49. Gastric Neuromuscular Function and Neuromuscular Disorders 50. Gastric Secretion 51. Helicobacter pylori Infection 52. Gastritis 53. Peptic Ulcer Disease 54. Adenocarcinoma of the Stomach and Other Gastric Tumors Section VII. Pancreas 55. Anatomy, Histology, Embryology, and Developmental Anomalies of the Pancreas 56. Pancreatic Secretion 57. Hereditary, Familial, and Genetic Disorders of the Pancreas and Pancreatic Disorders in Childhood 58. Acute Pancreatitis 59. Chronic Pancreatitis 60. Pancreatic Cancer, Cystic Pancreatic Neoplasms, and Other Nonendocrine Pancreatic Tumors 61. Endoscopic Treatment of Pancreatic Disease Section VIII. Biliary Tract 62. Anatomy, Histology, Embryology, Developmental Anomalies, and Pediatric Disorders of the Biliary Tract 63. Biliary Tract Motor Function and Dysfunction 64. Bile Secretion and the Enterohepatic Circulation 65. Gallstone Disease 66. Treatment of Gallstone Disease 67. Acalculous Biliary Pain, Acute Acalculous Cholecystitis, Cholesterolosis, Adenomyomatosis, and Gallbladder Polyps 68. Primary Sclerosing Cholangitis and Recurrent Pyogenic Cholangitis 69. Tumors of the Bile Ducts, Gallbladder, and Ampulla 70. Endoscopic and Radiologic Treatment of Biliary Disease Section IX. Liver71. Embryology, Anatomy, Histology, and Developmental Anomalies of the Liver 72. Liver Physiology and Energy Metabolism 73. Liver Chemistry and Function Tests 74. Overview of Cirrhosis 75. Hemochromatosis 76. Wilson Disease 77. Other Inherited Metabolic Disorders of the Liver 78. Hepatitis A 79. Hepatitis B 80. Hepatitis C 81. Hepatitis D 82. Hepatitis E 83. Hepatitis Caused by Other Viruses 84. Bacterial, Parasitic, and Fungal Infections of the Liver, including Liver Abscess 85. Vascular Diseases of the Liver 86. Alcoholic Liver Disease 87. Nonalcoholic Fatty Liver Disease 88. Hepatic Drug Metabolism and Liver Disease Caused by Drugs 89. Liver Disease Caused by Anesthetics, Chemicals, Toxins, and Herbal Preparations 90. Autoimmune Hepatitis 91. Primary Biliary Cirrhosis 92. Portal Hypertension and Variceal Bleeding 93. Ascites and Spontaneous Bacterial Peritonitis 94. Hepatic Encephalopathy, Hepatorenal Syndrome, Hepatopulmonary Syndrome, and Other Systemic Complications of Liver Disease 95. Acute Liver Failure 96. Hepatic Tumors and Cysts 97. Liver Transplantation Section X. Small and Large Intestine 98. Anatomy, Histology, Embryology, and Developmental Anomalies of the Small and Large Intestine 99. Small Intestinal Motor and Sensory Function and Dysfunction 100. Colonic Motor and Sensory Function and Dysfunction 101. Intestinal Electrolyte Absorption and Secretion 102. Digestion and Absorption of Dietary Fat, Carbohydrate, and Protein 103. Intestinal Digestion and Absorption of Micronutrients 104. Maldigestion and Malabsorption 105. Small Intestinal Bacterial Overgrowth 106. Short Bowel Syndrome 107. Celiac Disease 108. Tropical Diarrhea and Malabsorption 109. Whipple's Disease 110. Infectious Enteritis and Proctocolitis 111. Food Poisoning 112. Antibiotic-Associated Diarrhea and Clostridium difficile Infection 113. Intestinal Protozoa 114. Intestinal Worms 115. Crohn's Disease 116. Ulcerative Colitis 117. Ileostomy, Colostomy, and Pouches 118. Intestinal Ischemia 119. Intestinal Ulcerations 120. Appendicitis 121. Diverticular Disease of the Colon 122. Irritable Bowel Syndrome 123. Intestinal Obstruction 124. Ileus and Pseudo-obstruction 125. Tumors of the Small Intestine 126. Colonic Polyps and Polyposis Syndromes 127. Colorectal Cancer 128. Other Diseases of the Colon and Rectum 129. Diseases of the Anorectum Section XI. Additional Treatments for Patients with Gastrointestinal and Liver Disease 130. Probiotics and Fecal Microbiota Transplantation 131. Complementary and Alternative Medicine 132. Palliative Care for Patients with Gastrointestinal and Hepatic Disease