A comprehensive summary of knowledge on experimental and clinical granulomatoses. * Covers the major aspects of the granulomatous response, providing the basis for the understanding of the overall granulomatous immune response and its resolution. * Provides an in-depth discussion of the mechanistic basis of inflammation in a number of representative granulomatous diseases, illustrates different cellular responses and immune mechanisms within the framework of the general granulomatous response. * Examines experimental treatments of mice by cell transfer between donor and recipient, infection of inflammatory/regulatory cytokines or cytokine-neutralizing antibodies, and use of mice genetically deficient in cytokine/chemokine production or cytokine/chemokine receptor expression. This title is published by the American Society for Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Table of Contents Contributors Preface 1. The Cellular Immunological Aspects of the Granulomatous Response, Dov L. Boros 2. Cytokines and Chemokines in Granulomatous Inflammation, Stephen W. Chensue and Steven L. Kunkel 3. Granuloma Formation in Mouse and Giunea Pig Models of Experimental Tuberculosis, Oliver C. Turner, Randall J. Basaraba, Anthony A. Frank, and Ian M. Orne 4. Cryptococcosis, David L. Goldman and Arturo Casadevall 5. Murine Leishmaniasis, Paul M. Kaye and Christian R. Engwerda 6. Murine Schistosomiasis, Thomas A. Wynn 7. Human Tuberculosis, Stephen K. Schwander and Jerrold J. Ellner 8. Human Leprosy, Linda B. Adams and James L. Krahenbuhl 9. Human Beryliosis, Andrew P. Fontenot and Lee S. Newman 10. Sarcoidosis, Carlo Agostini and Gianpietro Semenzato 11. Crohn's Disease, Joel V. Weinstock Index