The 5th edition of this indispensable resource captures the latest insights in neonatal neurology in a totally engaging, readable manner. World authority Dr. Joseph Volpe has completely revised his masterwork from cover to cover, describing everything from the most up-to-the-minute discoveries in genetics through the latest advances in the diagnosis and management of neurologic disorders. He delivers all the clinical guidance you need to provide today's most effective care for neonates with neurological conditions.Provides comprehensive coverage of neonatal neurology, solely written by the field's founding expert, Dr. Joseph Volpe - for a masterful, cohesive source of answers to any question that arises in your practice. Focuses on clinical evaluation and management, while also examining the many scientific and technological advances that are revolutionizing neonatal neurology. Organizes disease-focused chapters by affected body region for ease of reference. Features a brand new, full-color design with hundreds of new figures, tables, algorithms, and micrographs. Includes two entirely new chapters: Neurodevelopmental Follow-Up and Stroke in the Newborn; a new section on Neonatal Seizures; and an extensively expanded section on Hypoxic-Ischemia and Other Disorders. Showcases the experience and knowledge of a new editorial team, led by Dr. Joseph Volpe and Dr. Terrie E. Inder, Chair of the Department of Pediatric Newborn Medicine at Brigham and Women's Hospital, all of whom bring a wealth of insight to this classic text. Offers comprehensive updates from cover to cover to reflect all of the latest information regarding the development of the neural tube; prosencephalic development; congenital hydrocephalus; cerebellar hemorrhage; neuromuscular disorders and genetic testing; and much more. Uses an improved organization to enhance navigation. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, Q&As, and references from the book on a variety of devices.
Unit I: Human Brain Development Overview 1. Neural Tube Development and Defects 2. Prosencephalic Development and Defects 3. Congenital Hydrocephalus 4. Cerebellar Development and Defects 5. Neuronal Proliferative Events and Defects 6. Neuronal Migrational Events and Defects 7. Organizational Events and Defects 8. Myelination Events and Defects Unit II: Neurological Evaluation Overview 9. Neurological Examination: Normal and Abnormal Features 10. Specialized Neurological Studies 11. Neurodevelopmental Followup Unit III: Neonatal Seizures Overview 12. Neonatal Seizures Unit IV: Hypoxic-ischemic and Related Disorders Overview 13. Pathophysiology General Principles 14. Encephalopathy of the Preterm - Neuropathology 15. Encephalopathy of the Preterm - Pathophysiology 16. Encephalopathy of the Preterm - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy 17. Intrauterine, Intrapartum Assessments in the Term Infant 18. Hypoxic Ischemic Injury in the Term Infant - Neuropathology 19. Hypoxic Ischemic Injury in the Term Infant - Pathophysiology 20. Hypoxic Ischemic Injury in the Term Infant - Clinical - Neurological Features, Diagnosis, Imaging, Prognosis, Therapy 21. Stroke in the Newborn Unit V: Intracranial Hemorrhage Overview 22. Intracranial/Hemorrhage - Supratentorial (Subdural, Subarachnoid, Intraventricular (Term Infant), Miscellaneous 23. Intracranial Hemorrhage Infratentorial/Cerebellar 24. Preterm IVH/Posthemorrhagic Hydrocephalus Unit VI: Metabolic Encephalopathies Overview 25. Glucose 26. Bilirubin 27. Amino acids 28. Organic acids Unit VII: Degenerative Disorders 29. Degenerative Disorders of the Newborn Unit VIII: Neuromuscular Disorders Overview 30. Evaluation, Specialized Studies 31. Arthrogryposis Multiplex Congenita 32. Levels Above Lower Motor Neuron to Neuromuscular Junction 33. Muscle Involvement and Restricted Disorders Unit IX: Intracranial Infections Overview 34. Viral, Protozoan and Related Intracranial Infections 35. Bacterial and Fungal Intracranial Infections Unit X: Perinatal Trauma 36. Injuries of Extracranial, Cranial, Intracranial, Spinal Cord and Peripheral Nervous System Structures Unit XI: Intracranial Mass Lesions 37. Brain Tumors and Vein of Galen Malformations Unit XII: Drugs and the Developing Nervous System Overview 38. Passive Addiction and Teratogenic Effects